PENTAGAMAVUNONE-1 INHIBITS AGGRESSIVE BREAST CANCER CELL PROLIFERATION THROUGH MITOTIC CATASTROPHE AND ROS-MEDIATED ACTIVITIES: IN VITRO AND IN VIVO STUDIES

Pentagamavunone-1 (PGV-1), an analog of curcumin, has been studied for its cytotoxic effects in 4T1, MCF7, MCF7/HER2, and T47D breast cancer cells.Its antiproliferative effect is partly mediated through G2/M arrest; however, its molecular mechanism during cell cycle progression remains unknown.In this study, we aimed to determine whether PGV-1 has

In mm-wave massive Multiple Input Multiple Output (MIMO) systems, in order to further improve the spectral efficiency of hybrid precoding in fully connected structure, an Alternate Minimization based HI POTENCY B COMPLEX on Gradient Descent (GD-AltMin) hybrid precoding algorithm is proposed.Firstly, the right singular vector of the channel matrix i

Electron bunches of high charge (up to 10 nC) Services are compressed in length in the Compact Linear Collider Test Facility magnetic chicane to less than 0.4 mm rms.The short bunches radiate coherently in the chicane magnetic field, and the horizontal and longitudinal phase space density distributions are affected.This paper reports the results of

Abstract Introduction Airway management is an important skill for all medical trainees to practice, particularly within difficult scenarios.To address this, we created this advanced airway management course for introducing advanced airway techniques to medical students, olive tree residents and fellows.It can also be used for faculty and practicing

Summary:.Managing cavity wounds that cannot be cleaned using standard irrigating solution is challenging.An immunocompromised patient with a horseshoe perianal abscess was selected to represent a heavy infection in cavity wounds.Diluted povidone-iodine was initially used to lavage the wounds, but the fever persisted and the irrigation was painful.H